bible.com/bible/100/eph.6.18.NASB1995

This verse introduces the general character of a believer’s prayer life: 1) “all prayer and petition” focuses on the variety; 2) “at all times” focuses on the frequency (cf. Ro 12:12; Php 4:6; 1Th 5:17); 3) “in the Spirit” focuses on submission, as we line up with the will of God (cf. Ro 8:26, 27); 4) “be on the alert” focuses on the manner (cf. Mt 26:41; Mk 13:33); 5) “all perseverance” focuses on the persistence (cf. Lk 11:9; 18:7, 8); and 6) “all the saints” focuses on the objects (cf. 1Sa 12:23).