www.bible.com/100/eph.6.18.nasb1995

Taken from MacArthur study Bible

This verse introduces the general character of a believer’s prayer life: 1) “all prayer and petition” focuses on the variety; 2) “at all times” focuses on the frequency (cf. Ro 12:12 ; Php 4:6 ; 1Th 5:17 ); 3) “in the Spirit” focuses on submission, as we line up with the will of God (cf. Ro 8:26 , 27 ); 4) “be on the alert” focuses on the manner (cf. Mt 26:41 ; Mk 13:33 ); 5) “all perseverance” focuses on the persistence (cf. Lk 11:9 ; 18:7 , 8 ); and 6) “all the saints” focuses on the objects (cf. 1Sa 12:23 ).